Medical Library · Gastroenterology

Chronic Gastritis

Chronic gastritis is a long-term inflammation of the stomach lining, which can be caused by infections, medications, or autoimmune conditions. Learn about symptoms, causes, treatment, and when to see a doctor.

Doctor discussing stomach health and chronic gastritis with a patient

Overview

Illustration of the human stomach and digestive system

The stomach lining can become inflamed over time, leading to chronic gastritis.

Chronic gastritis is a persistent inflammation of the stomach lining that can damage the stomach's protective layer. It can be erosive or non-erosive and can lead to complications if left untreated.

Unlike acute gastritis, which comes on suddenly and usually resolves quickly, chronic gastritis develops gradually and may persist for months or even years. Many people with chronic gastritis have mild symptoms or none at all, while others experience significant discomfort and complications.

Symptoms

Person experiencing abdominal discomfort and nausea

Some people may have no symptoms. Others may experience:

  • Dull pain or discomfort in the upper abdomen
  • Nausea and occasional vomiting
  • Bloating and a feeling of fullness after eating
  • Loss of appetite and unintended weight loss
  • Indigestion or heartburn
  • Black, tarry stools or blood in vomit (a sign of bleeding — seek urgent care)
When to seek urgent care: Vomiting blood, black stools, severe abdominal pain, or unexplained weight loss require immediate medical attention.

Causes

Laboratory testing for H. pylori and stomach conditions

Common causes of chronic gastritis include:

  • Helicobacter pylori (H. pylori) infection — the most common cause worldwide
  • Long-term use of NSAIDs such as ibuprofen, aspirin, or naproxen
  • Excessive alcohol consumption
  • Autoimmune disorders (autoimmune metaplastic atrophic gastritis)
  • Smoking and chronic stress
  • Bile reflux and other digestive conditions

Treatment

Medications and treatment plan for chronic gastritis

Treatment depends on the underlying cause and may include:

  • Acid-reducing medications — proton pump inhibitors (PPIs) or H2 blockers
  • Antibiotics to eradicate H. pylori (usually a combination regimen)
  • Stopping NSAIDs and reducing alcohol intake
  • Lifestyle changes — smaller meals, avoiding trigger foods, quitting smoking
  • Vitamin B12 supplementation for autoimmune gastritis
  • Regular monitoring with endoscopy in high-risk cases

When to See a Doctor

If you have persistent abdominal pain, nausea, or vomiting, or if you have signs of bleeding (blood in vomit or stools), see a doctor promptly. You should also seek medical advice if you experience unexplained weight loss, difficulty swallowing, or symptoms that do not improve with over-the-counter remedies.

Red flags: Blood in vomit or stool, severe pain, difficulty swallowing, or unintentional weight loss — these require urgent medical evaluation.